Emergency treatment of acute anaphylaxis

Emergency treatment of acute anaphylaxis (under expert supervision),

Management should start with airway, breathing, circulation (ABC) followed by administration of IM adrenaline

  • By intramuscular injection of adrenaline injection 1 in 1000 (1 mg/mL) for the emergency treatment of anaphylaxis.

  • Anterolateral aspect of the middle third of the thigh

  • doses may be repeated several times if necessary at 5 minute intervals


For Child 1 month–5 years 150 micrograms (0.15ml of 1 in 1000 adrenaline)

For Child 6–11 years 300 micrograms (0.3 ml of 1 in 1000 adrenaline)

For Child 12–17 years 500 micrograms (0.5 ml of 1 in 1000 adrenaline)

For Adult 500 micrograms (0.5 ml of 1 in 1000 adrenaline)

Adrenaline should be followed by parenteral chlorphenamine 10mg (slow iv or im) and then hydrocortisone 200mg (slow iv or im)

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Dr Rajesh Varmaanaphylaxis